Vegetables of the nightshade family contain cholinesterase inhibiting glycoalkaloids and steroid alkaloids including, among others, capsaicin in peppers, nicotine in tobacco, solanine in aubergines and potatoes and tomatine in tomatoes. The glycoalkaloids in potatoes are also known to contribute to Irritable Bowel Syndrome (IBS) and negatively affect intestinal permeability which can also lead to an over reactive immune system.
Many who suffer with arthritis or inflammatory diseases such as fibromyalgia, lupus, rheumatism and other musculoskeletal pain disorders have found that consuming foods that contain glycoalkaloids worsens their condition. Alkaloids for other health problems including
muscle pain, poor healing and other inflammatory conditions.
Members of the nightshade family
Other plants that contain the alkaloid solanine
Symptoms of glycoalkaloids and steroid alkaloids intolerance may dissipate in a few hours or days if ingestion is stopped based on the sensitivity of the individual, the amount of nightshades consumed on a regular basis and their level of inflammation. However for some heavy consumers of nightshades the process of inflammation and pain reduction can take up to three months. It is a good idea to try eliminating all nightshades from the diet for three months to see if symptoms improve.
Nutritious alternatives to potatoes